000 02904cam a22003617 4500
001 w23900
003 NBER
005 20211020104753.0
006 m o d
007 cr cnu||||||||
008 210910s2017 mau fo 000 0 eng d
100 1 _aHult, Kristopher J.
245 1 0 _aMeasuring the Potential Health Impact of Personalized Medicine:
_bEvidence from MS Treatments /
_cKristopher J. Hult.
260 _aCambridge, Mass.
_bNational Bureau of Economic Research
_c2017.
300 _a1 online resource:
_billustrations (black and white);
490 1 _aNBER working paper series
_vno. w23900
500 _aOctober 2017.
520 3 _aIndividuals respond to pharmaceutical treatments differently due to the heterogeneity of patient populations. This heterogeneity can make it difficult to determine how efficacious or burdensome a treatment is for an individual patient. Personalized medicine involves using patient characteristics, therapeutics, or diagnostic testing to understand how individual patients respond to a given treatment. Personalized medicine increases the health impact of existing treatments by improving the matching process between patients and treatments and by improving a patient's understanding of the risk of serious side effects. In this paper, I compare the health impact of new treatment innovations with the potential health impact of personalized medicine. I find that the impact of personalized medicine depends on the number of treatments, the correlation between treatment effects, and the amount of noise in a patient's individual treatment effect signal. For multiple sclerosis treatments, I find that personalized medicine has the potential to increase the health impact of existing treatments by roughly 50 percent by informing patients of their individual treatment effect and risk of serious side effects.
530 _aHardcopy version available to institutional subscribers
538 _aSystem requirements: Adobe [Acrobat] Reader required for PDF files.
538 _aMode of access: World Wide Web.
588 0 _aPrint version record
690 7 _aI1 - Health
_2Journal of Economic Literature class.
690 7 _aI10 - General
_2Journal of Economic Literature class.
690 7 _aI11 - Analysis of Health Care Markets
_2Journal of Economic Literature class.
690 7 _aO3 - Innovation • Research and Development • Technological Change • Intellectual Property Rights
_2Journal of Economic Literature class.
690 7 _aO31 - Innovation and Invention: Processes and Incentives
_2Journal of Economic Literature class.
710 2 _aNational Bureau of Economic Research.
830 0 _aWorking Paper Series (National Bureau of Economic Research)
_vno. w23900.
856 4 0 _uhttps://www.nber.org/papers/w23900
856 _yAcceso en lĂ­nea al DOI
_uhttp://dx.doi.org/10.3386/w23900
942 _2ddc
_cW-PAPER
999 _c324223
_d282785